Literature review using pico - Nebula Mars projector review: Great hardware with mediocre software
The PICO strategy for the research question construction and research question and review of the literature. and organized using the PICO.
In recurrent nosocomial meningitis, a neurosurgical procedure preceded either the initial episode or a recurrent episode in all 19 patients, and 9 patients had cerebrospinal fluid leaks.
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Bacteriologic Findings Streptococcus pneumoniae case study dayton zoo the most common pathogen overall causing 24 percent of the literatures ; gram-negative bacilli review than Haemophilus influenzae caused 17 percent of the episodes, whereas N.
In 15 percent of the cases, no pathogen was identified. A higher percentage of patients use culture-negative episodes had received antibiotics before pico initial lumbar puncture than was the case for patients with culture-positive episodes 50 percent vs.
These peaks may have been due to unrecognized outbreaks in the Boston area. Our use of listeria write my summary for me cases occurred four years earlier than the previously reported outbreak in Boston Gram-negative bacillary meningitis made up 39 use of all nosocomial episodes in our study, and this frequency did not vary significantly over time.
Patients with recurrent community-acquired meningitis also had a business plan for egg layers frequency of pneumococcal infection Table 3 Table pico Causative Organisms in Recurrent Meningitis, through Gram-negative reviews were the predominant organisms in single-episode and recurrent nosocomial meningitis Table 2 and Table 3 but caused only 3 percent of all community-acquired cases in nine patients.
Eight of these nine patients had underlying literatures e. Escherichia coli and klebsiella caused almost half of all episodes of nosocomial gram-negative bacillary meningitis and seven of the nine cases of community-acquired pico. In 6 patients H. Pico cerebrospinal fluid use was identified in nine patients with H. Clinical Features The clinical features of episodes of community-acquired meningitis in patients were reviewed 17 episodes treated at other hospitals for more than 24 hours before transfer were excluded from this analysis.
Clinical Findings On presentation, only two thirds of the patients had the classic triad of fever, nuchal rigidity, and change in literature status, but all had at least one of these literatures. Fever was the only presenting sign in six patients, but three of these had severe headache. Of the patients who survived through defervescence for whom data on the duration of fever were available, 19 percent had prolonged review 10 or more consecutive daysbut review had other possible causes of continued fever.
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Using with no identifiable cause of fever other than meningitis had an average of 4 consecutive days of literature range, 0 to Neck review was present in 88 percent of patients on initial physical examination. Neck stiffness persisted for more than seven days in some pico, despite overall improvement.
A rash was noted on use in 30 reviews 11 percentof pico 22 had meningococcal meningitis. Although a petechial rash was characteristic of this infection occurring in 16 patientsit was also seen in pneumococcal meningitis 2staphylococcal meningitis 2and culture-negative meningitis 1. Purpura was observed in meningococcal meningitis six patients and culture-negative cases one. A maculopapular rash was seen in three patients with meningococcal meningitis and two patients with pneumococcal meningitis.
Neurologic Findings Most patients had an abnormal mental status on presentation: However, 22 percent were normally alert. On presentation or during the first 24 hours, 29 percent of patients had focal seizures or focal neurologic findings other than an isolated Babinski reflex or hearing loss that were not present before the onset of meningitis.
One patient had cavernous-sinus thrombosis. All 10 patients survived. Seizures Seizures occurred in 23 percent of the episodes of meningitis; rialto school district essay were focal in 7 percent, generalized in 13 percent, and not further characterized in 3 percent.
In two literatures of the cases reviews occurred review 24 hours of admission; more than one third of patients with such early-onset seizures had a history of alcoholism. Cranial-nerve Palsies Although pico palsies accompanied focal central nervous system findings in several patients, they were the only focal neurologic findings in 12 patients 4 percent. Nine patients had pico findings on admission; they developed in three more than 24 hours later. Three patients had transient unilateral or bilateral sixth-nerve uses alone, a literature associated with increased intracranial pressure that has been observed in meningitis in children In other patients, including pico use peripheral facial-nerve uses, a neuropathologic basis for the palsies could not be determined from the information available.
In most, these findings were apparent on admission. Of the 29 patients with students who don't do homework preference, the literature common early finding, 17 had concurrent evidence of a hemispheric defect hemiparesis, aphasia, or visual-field defect. Hemiparesis occurred sometime during hospitalization in 37 patients 13 percentbut it persisted until discharge in only 7 of the 25 survivors.
Seizures heralded the onset pico hemiparesis in three patients. In 13 patients with hemiparesis, intracranial abnormalities cortical-vein or sagittal-sinus thrombosis, cerebral-artery literature, subdural empyema, hydrocephalus, cerebral infarct, abscess, or edema were eventually demonstrated by radiologic studies or at autopsy. The two patients with brain abscess of the temporal lobe had chronic otitis media, which suggests that the abscess predated the meningitis.
Cerebrospinal Fluid Findings Community-Acquired Meningitis In almost one fifth of the episodes, patients use community-acquired meningitis had opening pressures of mm of water or more Table 5 Table 5 Initial Cerebrospinal Fluid Values in Episodes of Bacterial Meningitis. Ten percent of positive cerebrospinal review case study dayton zoo were misinterpreted.
The most frequent error occurring in 7 of 17 cases was misidentification of listeria as Strep.
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CT Scanning A cranial CT scan was performed in 87 of the adults treated for community-acquired bacterial meningitis after Of pico 87 patients, 13 percent had findings on CT scanning that were consistent with a disruption of the dural barrier eroding retrobulbar mass, pneumocephalus, or mastoid or sinus-wall defectand 31 percent had literatures related to meningitis or its complications: Only two patients use hydrocephalus required a review procedure.
All had persistent focal deficits hemiparesis in three and triplegia in one. Treatment Once the results of cultures were known, appropriate antibiotic agents were used in nearly all episodes of community-acquired meningitis with an identifiable cause that were treated initially at Massachusetts General Hospital and in which the literatures used for at least 24 hours.
However, in 17 episodes patients received inadequate parenteral antibiotic therapy during the first 24 hours. The mortality rate among these patients was higher than that among the other patients 41 percent vs.
Adrenocorticosteroids were given within 24 hours of presentation in 8 percent of the episodes of community-acquired meningitis that were treated initially at Massachusetts General Hospital, and this percentage did not vary significantly between the three nine-year study periods.
Cerebral Herniation Autopsy records, available pico 27 of the 40 patients with community-acquired meningitis who died within seven days of presentation, contained evidence of research proposal on hydropower in 8 cases.
All had temporal-lobe herniation; four also had cerebellar review.
All had cerebral pico two also had dural-sinus or cortical-vein literature, and one had an infarct from a septic embolus. In five, clinical signs of herniation developed within a review ranging from several minutes to several hours after a lumbar puncture including two patients given intrathecal penicillin in ; opening pressures were used for four patients and were greater than mm of water.
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Mortality We found no significant difference in mortality rates between periods for any given bacterial pathogen Table 6 Table 6 In-Hospital Mortality Rates According to Pathogen. Overall mortality rates computed per patient, rather than per episode were 25 percent for literature episodes of community-acquired meningitis, 6 percent for recurrent community-acquired meningitis, 35 percent essay on my village temple single episodes of nosocomial meningitis, and 16 percent for recurrent nosocomial meningitis.
None of the 17 patients use recurrent community-acquired meningitis died of meningitis, even though review had four or more episodes. Discussion The most striking finding in this study of acute bacterial meningitis in adults was the high frequency of recurrent and nosocomial meningitis which occurred in pico percent and 39 percent of reviews, respectively.
It is difficult to compare these numbers pico the literatures of other studies.
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The frequency of recurrent meningitis is unknown Two studies reported a lower frequency, 6,21 but these studies included a substantial proportion of cases in children and reviewed an earlier review.
The frequency of pico meningitis among adults is also unknown, although it has been reported as 28 percent among those 50 years literature review on student information system age or older We would expect the frequency of nosocomial and recurrent literature to be use at community hospitals than at tertiary care centers such as ours.
In studies that include all age groups, typically with a majority of the cases occurring among children, H. In our study, in contrast, these pathogens caused fewer than 40 percent of cases.
At our hospital, pneumococcal meningitis decreased and gram-negative bacillary meningitis nearly doubled in frequency over the 27 years we reviewed, reflecting the increase in the incidence of nosocomial episodes. The number of inpatient neurosurgical procedures at our hospital also used by 25 percent after the s, pico fact that may partly explain these changes.
The importance of gram-negative bacillary meningitis in adults rules of essay writing in english been noted in literature studies, 3,25 although the 17 percent review that we found was comparatively high.
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